A 90 kg patient is prescribed 25 mg/kg/day. Is this within the safe daily limit of 1,500 mg/day?

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Multiple Choice

A 90 kg patient is prescribed 25 mg/kg/day. Is this within the safe daily limit of 1,500 mg/day?

Dosing based on weight guides how much a patient should receive each day, and there is a maximum safe daily limit to prevent toxicity. For a patient who weighs 90 kg, a dose of 25 mg per kg per day computes to 25 × 90 = 2,250 mg per day. The established safe daily limit is 1,500 mg per day, so 2,250 mg exceeds that limit. Therefore this dose is not within the safe daily limit. If the goal is to stay within 1,500 mg/day, the dose would need to be adjusted to about 16.7 mg/kg/day (1,500 mg ÷ 90 kg), or capped at 1,500 mg/day using appropriate practical dosing.

Dosing based on weight guides how much a patient should receive each day, and there is a maximum safe daily limit to prevent toxicity. For a patient who weighs 90 kg, a dose of 25 mg per kg per day computes to 25 × 90 = 2,250 mg per day. The established safe daily limit is 1,500 mg per day, so 2,250 mg exceeds that limit. Therefore this dose is not within the safe daily limit. If the goal is to stay within 1,500 mg/day, the dose would need to be adjusted to about 16.7 mg/kg/day (1,500 mg ÷ 90 kg), or capped at 1,500 mg/day using appropriate practical dosing.

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