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Multiple Choice

Glycolysis occurs in the cytoplasm and is anaerobic. Which option correctly states this?

Glycolysis happens in the cytoplasm and does not require oxygen, so it can run under anaerobic conditions. It occurs in the cytosol, converting one glucose into two pyruvate molecules and yielding a net gain of two ATP and two NADH. Because oxygen isn’t needed, glycolysis can proceed whether oxygen is present or not. If oxygen is available, the pyruvate can move on to the mitochondria for aerobic respiration, but glycolysis itself remains an oxygen-independent process. This makes the statement true.

Glycolysis happens in the cytoplasm and does not require oxygen, so it can run under anaerobic conditions. It occurs in the cytosol, converting one glucose into two pyruvate molecules and yielding a net gain of two ATP and two NADH. Because oxygen isn’t needed, glycolysis can proceed whether oxygen is present or not. If oxygen is available, the pyruvate can move on to the mitochondria for aerobic respiration, but glycolysis itself remains an oxygen-independent process. This makes the statement true.