In the term hypoglycemia, what does the suffix -emia represent?

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The suffix -emia signals a condition or state of the blood. In hypoglycemia, glycemia refers to the glucose level in the blood, and hypo- means low. So the term describes a blood condition characterized by low blood sugar. That’s why the correct interpretation is a blood condition. Inflammation is marked by -itis, pain by -algia, and disease isn’t conveyed by a suffix here, so they don’t fit the meaning of -emia.